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An NIH-funded postdoctoral position is immediately available in the laboratory of Dr. Barbara Rehermann, Immunology Section, Liver Diseases Branch, NIDDK, NIH in Bethesda, Maryland, USA to conduct translational and basic studies on immune responses to viruses, in particular those that affect the liver, and the regulation of systemic and hepatic immune responses by the gut microbiome. 

       The laboratory conducts translational studies with well-defined with chronic viral hepatitis to evaluate immune-modulatory therapies for hepatitis B and hepatitis D virus infection and protective immune responses in hepatitis C virus and hepatitis D virus infection (Gastroenterology2019;156:369-383; Gastroenterology153:1392-1403:2017; Immunity, 40:13-24, 2014). 

The laboratory also conducts basic and translational studies to understand the regulation of inflammation and immunity by the gut microbiome based on the concept that natural microbiota co-evolved with their respective hosts under evolutionary pressure and confer host fitness-promoting.  We are using a mouse model that combines the tractable genetics of the standard laboratory mice with the fitness-promoting traits of microbes (Cell 171: 1015-1028, 2017; Science 2019 in press). This model is allows us to identify mechanisms of host physiology and disease resistance in the natural world, to improve preclinical efficacy and safety testing, and to more accurately reflect diseases in humans (see https://www.youtube.com/watch?v=SbFM7NC8yUg).

The postdoctoral position provides excellent training opportunities in human and/or mouse immunology, and opportunities for extensive collaborations within the NIH research community.  

Applicants must have a Ph.D., M.D. or D.V.M. degree, and fewer than 3 years of postdoctoral training.  Previous experience in multiparameter flow cytometry, molecular biology, gene expression analysis, intestinal cell isolation, and/or mouse models of disease is desired. Appointees may be US citizens, resident aliens, or non-resident aliens with or eligible to obtain a valid employment authorized visa.  Salary is commensurate with research experience and accomplishments.  Applications from women, minorities and persons with disabilities are strongly encouraged. The application should include CV and contact information for three references.

 

 

Kontakt: 
Barbara Rehermann, MD, Chief, Immunology Section, Liver Diseases Branch, NIDDK National Institutes of Health, DHHS, Bldg 10, Room 9B16, 10 Center Drive, Bethesda, MD 20892-1800, USA, Email: Rehermann@nih.gov